Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine

Modified Vaccinia Ankara (MVA) is a highly attenuated poxvirus vector that is widely used to develop vaccines for infectious diseases and cancer. We developed a novel vaccine platform based on a unique three-plasmid system to efficiently generate recombinant MVA vectors from chemically synthesized D...

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Publicado en:bioRxiv
Autores principales: Chiuppesi, Flavia, Salazar, Marcela d’Alincourt, Contreras, Heidi, Nguyen, Vu H, Martinez, Joy, Park, Soojin, Nguyen, Jenny, Kha, Mindy, Iniguez, Angelina, Zhou, Qiao, Kaltcheva, Teodora, Levytskyy, Roman, Ebelt, Nancy D, Kang, Tae Hyuk, Wu, Xiwei, Rogers, Thomas, Manuel, Edwin R, Shostak, Yuriy, Diamond, Don J, Wussow, Felix
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337387/
https://ncbi.nlm.nih.gov/pubmed/32637957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.01.183236
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