Depot medroxyprogesterone acetate (Depo-Provera) administration increases cervical CCR5(+)CD4(+) T cells and induces immunosuppressive milieu at the cervicovaginal mucosa: a 3-month longitudinal study

OBJECTIVES: Depot medroxyprogesterone acetate (Depo-Provera) is the most commonly used injectable hormone contraceptive in Sub-Sahara Africa where HIV incidence is high. We determined the impact of Depo-Provera on cervical immune cells and mediators in healthy women. METHODS: In this longitudinal st...

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Gepubliceerd in:AIDS
Hoofdauteurs: Tasker, Carley, Pizutelli, Vanessa, Lo, Yungtai, Ramratnam, Bharat, Roche, Natalie E., Chang, Theresa L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337252/
https://ncbi.nlm.nih.gov/pubmed/31972606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002475
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