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Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium

The proinflammatory cytokine IL-1β is a significant risk factor in cardiovascular disease that can be targeted to reduce major cardiovascular events. IL-1β expression and release are tightly controlled by changes in intracellular Ca(2+) [Ca(2+)](i) which has been associated with ATP release and puri...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yang, Yang, Delalio, Leon, Best, Angela K, Macal, Edgar, Milstein, Jenna, Donnelly, Iona, Miller, Ashley M., McBride, Martin, Shu, Xiaohong, Koval, Michael, Isakson, Brant E., Johnstone, Scott R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336877/
https://ncbi.nlm.nih.gov/pubmed/32312847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901089
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