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Missense NR2F1 variant in monozygotic twins affected with the Bosch–Boonstra–Schaaf optic atrophy syndrome

BACKGROUND: The Bosch‐Boonstra‐Schaaf optic atrophy syndrome (BBSOAS) is an autosomal‐dominant disorder (OMIM615722) mostly characterized by optic atrophy and/or hypoplasia, mild intellectual disability, hypotonia, seizures/infantile epilepsy. This disorder is caused by loss‐of‐function alterations...

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Dades bibliogràfiques
Publicat a:Mol Genet Genomic Med
Autors principals: Mio, Catia, Fogolari, Federico, Pezzoli, Laura, D’Elia, Angela V., Iascone, Maria, Damante, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336747/
https://ncbi.nlm.nih.gov/pubmed/32412696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1278
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