IL-6 Deficiency Exacerbates Allergic Asthma and Abrogates the Protective Effect of Allergic Inflammation against Streptococcus pneumoniae Pathogenesis

Allergic asthma (AA) is characterized as a Th2-biased airway inflammation that can develop lung inflammation and remodeling of the respiratory tract. Streptococcus pneumoniae is a major respiratory pathogen, causing noninvasive (otitis media and pneumonia) and invasive diseases (sepsis) in humans. W...

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Vydáno v:J Immunol
Hlavní autoři: Schmit, Taylor, Ghosh, Sumit, Mathur, Ram Kumar, Barnhardt, Tyler, Ambigapathy, Ganesh, Wu, Min, Combs, Colin, Khan, M. Nadeem
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2020
Témata:
Infectious Disease and Host Response
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336542/
https://ncbi.nlm.nih.gov/pubmed/32540994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900755
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