The endothelial basement membrane acts as a checkpoint for entry of pathogenic T cells into the brain

The endothelial cell basement membrane (BM) is a barrier to migrating leukocytes and a rich source of signaling molecules that can influence extravasating cells. Using mice lacking the major endothelial BM components, laminin 411 or 511, in murine experimental autoimmune encephalomyelitis (EAE), we...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Zhang, Xueli, Wang, Ying, Song, Jian, Gerwien, Hanna, Chuquisana, Omar, Chashchina, Anna, Denz, Cornelia, Sorokin, Lydia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2020
Onderwerpen:
Brief Definitive Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336306/
https://ncbi.nlm.nih.gov/pubmed/32379272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191339
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