Calsyntenin-3 interacts with both α- and β-neurexins in the regulation of excitatory synaptic innervation in specific Schaffer collateral pathways

Calsyntenin-3 (Clstn3) is a postsynaptic adhesion molecule that induces presynaptic differentiation via presynaptic neurexins (Nrxns), but whether Nrxns directly bind to Clstn3 has been a matter of debate. Here, using LC–MS/MS–based protein analysis, confocal microscopy, RNAscope assays, and electro...

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Vydáno v:J Biol Chem
Hlavní autoři: Kim, Hyeonho, Kim, Dongwook, Kim, Jinhu, Lee, Hee-Yoon, Park, Dongseok, Kang, Hyeyeon, Matsuda, Keiko, Sterky, Fredrik H., Yuzaki, Michisuke, Kim, Jin Young, Choi, Se-Young, Ko, Jaewon, Um, Ji Won
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335786/
https://ncbi.nlm.nih.gov/pubmed/32434929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013077
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