Role of folding kinetics of secondary structures in telomeric G-overhangs in the regulation of telomere maintenance in Saccharomyces cerevisiae

The ends of eukaryotic chromosomes typically contain a 3′ ssDNA G-rich protrusion (G-overhang). This overhang must be protected against detrimental activities of nucleases and of the DNA damage response machinery and participates in the regulation of telomerase, a ribonucleoprotein complex that main...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jurikova, Katarina, Gajarsky, Martin, Hajikazemi, Mona, Nosek, Jozef, Prochazkova, Katarina, Paeschke, Katrin, Trantirek, Lukas, Tomaska, Lubomir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335780/
https://ncbi.nlm.nih.gov/pubmed/32385108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012914
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