Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array

The efficacy and safety of lenvatinib (LEN) as a second/third-line treatment for unresectable hepatocellular carcinoma (HCC) after sorafenib (SOR) therapy remains unknown. We evaluated the outcomes of second/third-line LEN treatment, investigated the sensitivity of a SOR-resistant HCC cell line (PLC...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Tomonari, Tetsu, Sato, Yasushi, Tanaka, Hironori, Tanaka, Takahiro, Fujino, Yasuteru, Mitsui, Yasuhiro, Hirao, Akihiro, Taniguchi, Tatsuya, Okamoto, Koichi, Sogabe, Masahiro, Miyamoto, Hiroshi, Muguruma, Naoki, Kagiwada, Harumi, Kitazawa, Masashi, Fukui, Kazuhiko, Horimoto, Katsuhisa, Takayama, Tetsuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335665/
https://ncbi.nlm.nih.gov/pubmed/32655838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27640
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