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O-glycosylation on cerebrospinal fluid and plasma apolipoprotein E differs in the lipid-binding domain

The O-glycoprotein apolipoprotein E (APOE), the strongest genetic risk factor for Alzheimer’s disease, associates with lipoproteins. Cerebrospinal fluid (CSF) APOE binds only high-density lipoproteins (HDLs), while plasma APOE attaches to lipoproteins of diverse sizes with binding fine-tuned by the...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Glycobiology
Päätekijät: Flowers, Sarah A, Grant, Oliver C, Woods, Robert J, Rebeck, G William
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335482/
https://ncbi.nlm.nih.gov/pubmed/31616924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz084
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