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Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo

We sought here to induce the excision of a large intragenic segment within the intact dystrophin gene locus, with the ultimate goal to elucidate dystrophin protein function and stability in striated muscles in vivo. To this end, we implemented an inducible-gene excision methodology using a floxed al...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Bez Batti Angulski, Addeli, Bauer, John, Cohen, Houda, Kobuke, Kazuhiro, Campbell, Kevin P., Metzger, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335168/
https://ncbi.nlm.nih.gov/pubmed/32620803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67372-0
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