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A novel theoretical framework reveals more than one voltage-sensing pathway in the lateral membrane of outer hair cells

Outer hair cell (OHC) electromotility amplifies acoustic vibrations throughout the frequency range of hearing. Electromotility requires that the lateral membrane protein prestin undergo a conformational change upon changes in the membrane potential to produce an associated displacement charge. The m...

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Bibliographic Details
Published in:J Gen Physiol
Main Authors: Farrell, Brenda, Skidmore, Benjamin L., Rajasekharan, Vivek, Brownell, William E.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335013/
https://ncbi.nlm.nih.gov/pubmed/32384538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912447
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