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Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafish
Cancer incidence increases exponentially with age when human telomeres are shorter. Similarly, telomerase reverse transcriptase (tert) mutant zebrafish have premature short telomeres and anticipate cancer incidence to younger ages. However, because short telomeres constitute a road block to cell pro...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7334448/ https://ncbi.nlm.nih.gov/pubmed/32554492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920049117 |
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