A novel terpenoid class for prevention and treatment of KRAS-driven cancers: Comprehensive analysis using in situ, in vitro and in vivo model systems

Inhibiting the disease progression in KRAS-driven cancers after diagnosis has been a difficult task for clinicians to manage due to lack of effective intervention/preventive therapies. KRAS-driven cancers depend on sustained KRAS-signaling. Although developing inhibitors of KRAS-signaling has proven...

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Dettagli Bibliografici
Pubblicato in:Mol Carcinog
Autori principali: Ganaie, Arsheed A., Siddique, Hifzur R., Sheikh, Ishfaq A., Parray, Aijaz, Wang, Lei, Panyam, Jayanth, Villalta, Peter W., Deng, Yibin, Konety, Badrinath R., Saleem, Mohammad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334075/
https://ncbi.nlm.nih.gov/pubmed/32291806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23200
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