Selective intrarenal delivery of mesenchymal stem cell-derived extracellular vesicles attenuates myocardial injury in experimental metabolic renovascular disease

BACKGROUND: Extracellular vesicles (EVs) deliver genes and proteins to recipient cells, and mediate paracrine actions of their parent cells. Intrarenal delivery of mesenchymal stem cell (MSC)-derived EVs preserves stenotic-kidney function and reduces release of pro-inflammatory cytokines in a swine...

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Publicat a:Basic Res Cardiol
Autors principals: Zhang, Lei, Zhu, Xiang-Yang, Zhao, Yu, Eirin, Alfonso, Liu, Lei, Ferguson, Christopher M., Tang, Hui, Lerman, Amir, Lerman, Lilach O.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333936/
https://ncbi.nlm.nih.gov/pubmed/31938859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-019-0772-8
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