Reverse swing‐M, phase 1 study of repurposing mebendazole in recurrent high‐grade glioma

BACKGROUND: Relapsed high‐grade glioma has dismal outcomes. Mebendazole has shown promising activity against glioma in in‐vitro and in‐vivo studies. Hence, we undertook a phase 1 study to repurpose mebendazole in the treatment of glioblastoma. METHODS: We conducted a phase 1 study (accelerated titra...

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發表在:Cancer Med
Main Authors: Patil, Vijay M., Bhelekar, Arti, Menon, Nandini, Bhattacharjee, Atanu, Simha, Vijai, Abhinav, Ram, Abhyankar, Anuja, Sridhar, Epari, Mahajan, Abhishek, Puranik, Ameya D., Purandare, Nilendu, Janu, Amit, Ahuja, Ankita, Krishnatry, Rahul, Gupta, Tejpal, Jalali, Rakesh
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
主題:
Clinical Cancer Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333848/
https://ncbi.nlm.nih.gov/pubmed/32400117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3094
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