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Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal

Mutation-derived neoantigens are taking central stage as a determinant in eliciting effective antitumor immune responses following adoptive T-cell therapies. These mutations are patient-specific, and their targeting calls for highly personalized pipelines. The promising clinical outcomes of tumor-in...

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Foilsithe in:Front Immunol
Main Authors: Bianchi, Valentina, Harari, Alexandre, Coukos, George
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333784/
https://ncbi.nlm.nih.gov/pubmed/32695101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01215
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