Selective Loss of Brain-Derived Neurotrophic Factor Exacerbates Brain Injury by Enhancing Neuroinflammation in Experimental Streptococcus pneumoniae Meningitis

Streptococcus pneumoniae meningitis is a life-threatening bacterial infection of the central nervous system (CNS), and its unfavorable prognosis usually results from an intense inflammatory response. Recent studies have shown that brain-derived neurotrophic factor (BDNF) mediates anti-inflammatory a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhao, Shengnan, Zhang, Zhijie, Xu, Danfeng, Wang, Yanfei, Li, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333737/
https://ncbi.nlm.nih.gov/pubmed/32676082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01357
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