Methoxyphenol derivatives as reversible inhibitors of myeloperoxidase as potential antiatherosclerotic agents

AIM: To evaluate new chemical entities, based on ferulic acid scaffolds, as reversible myeloperoxidase inhibitors (MPOI). METHODOLOGY & RESULTS: In silico docking studies are performed with MPO protein as a target for several ferulic acid analogs followed by multiple in vitro assays to validate...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Jayaraj, Premkumar, Narasimhulu, Chandrakala A, Maiseyeu, Andrei, Durairaj, Rekha, Rao, Shashidhar, Rajagopalan, Sanjay, Parthasarathy, Sampath, Desikan, Rajagopal
Formato: Artigo
Idioma:Inglês
Publicado em: Newlands Press Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333589/
https://ncbi.nlm.nih.gov/pubmed/31769316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2019-0080
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