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A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter

CD154 (CD40-ligand) is a critical immune regulator. CD154 expression is tightly regulated and largely restricted to activated CD4 T cells. Using DNase I hypersensitivity site (HSS) mapping, we identified two novel HSS mapping to the human CD154 promoter element and just upstream. Both HSS were activ...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Brunner, M, Zhang, M, Genin, A, Ho, I-C, Cron, RQ
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333362/
https://ncbi.nlm.nih.gov/pubmed/18719603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2008.67
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