Severe COVID-19: NLRP3 Inflammasome Dysregulated

SARS-CoV-2 might directly activate NLRP3 inflammasome resulting in an endogenous adjuvant activity necessary to mount a proper adaptive immune response against the virus. Heterogeneous response of COVID-19 patients could be attributed to differences in not being able to properly downregulate NLRP3 i...

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Bibliographic Details
Published in:Front Immunol
Main Authors: van den Berg, Daan F., te Velde, Anje A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332883/
https://ncbi.nlm.nih.gov/pubmed/32670297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01580
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