The Vacuolating Autotransporter Toxin (Vat) of Escherichia coli Causes Cell Cytoskeleton Changes and Produces Non-lysosomal Vacuole Formation in Bladder Epithelial Cells

Urinary tract infections (UTIs) affect more than 150 million people, with a cost of over 3.5 billion dollars, each year. Escherichia coli is associated with 70–80% of UTIs. Uropathogenic E. coli (UPEC) has virulence factors including adhesins, siderophores, and toxins that damage host cells. Vacuola...

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Udgivet i:Front Cell Infect Microbiol
Main Authors: Díaz, Juan Manuel, Dozois, Charles M., Avelar-González, Francisco Javier, Hernández-Cuellar, Eduardo, Pokharel, Pravil, de Santiago, Alfredo Salazar, Guerrero-Barrera, Alma Lilian
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cellular and Infection Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332727/
https://ncbi.nlm.nih.gov/pubmed/32670893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00299
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