Arsenic trioxide induces regulatory functions of plasmacytoid dendritic cells through interferon-α inhibition

Arsenic trioxide (As(2)O(3)) is recently found to have therapeutic potential in systemic sclerosis (SSc), a life-threatening multi-system fibrosing autoimmune disease with type I interferon (IFN-I) signature. Chronically activated plasmacytoid dendritic cells (pDCs) are responsible for IFN-I secreti...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Ye, Yishan, Ricard, Laure, Siblany, Lama, Stocker, Nicolas, De Vassoigne, Frédéric, Brissot, Eolia, Lamarthée, Baptiste, Mekinian, Arsène, Mohty, Mohamad, Gaugler, Béatrice, Malard, Florent
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332672/
https://ncbi.nlm.nih.gov/pubmed/32642412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.01.016
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