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Natural Selection Shapes Codon Usage in the Human Genome
Synonymous codon usage has been identified as a determinant of translational efficiency and mRNA stability in model organisms and human cell lines. However, whether natural selection shapes human codon content to optimize translation efficiency is unclear. Furthermore, aside from those that affect s...
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| Udgivet i: | Am J Hum Genet |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7332603/ https://ncbi.nlm.nih.gov/pubmed/32516569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.05.011 |
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