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Structural aspects of the human small heat shock proteins related to their functional activities

Small heat shock proteins function as chaperones by binding unfolding substrate proteins in an ATP-independent manner to keep them in a folding-competent state and to prevent irreversible aggregation. They play crucial roles in diseases that are characterized by protein aggregation, such as neurodeg...

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Vydáno v:Cell Stress Chaperones
Hlavní autor: Boelens, Wilbert C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332592/
https://ncbi.nlm.nih.gov/pubmed/32253739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-020-01093-1
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