Atomic model for the membrane-embedded V(O) motor of a eukaryotic V-ATPase

Vacuolar-type ATPases (V-ATPases) are ATP-powered proton pumps involved in processes such as endocytosis, lysosomal degradation, secondary transport, TOR signalling, and osteoclast and kidney function. ATP hydrolysis in the soluble catalytic V(1) region drives proton translocation through the membra...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Mazhab-Jafari, Mohammad T., Rohou, Alexis, Schmidt, Carla, Bueler, Stephanie A., Benlekbir, Samir, Robinson, Carol V., Rubinstein, John L.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332345/
https://ncbi.nlm.nih.gov/pubmed/27776355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19828
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