Atomic model for the membrane-embedded V(O) motor of a eukaryotic V-ATPase

Vacuolar-type ATPases (V-ATPases) are ATP-powered proton pumps involved in processes such as endocytosis, lysosomal degradation, secondary transport, TOR signalling, and osteoclast and kidney function. ATP hydrolysis in the soluble catalytic V(1) region drives proton translocation through the membra...

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Bibliographic Details
Published in:Nature
Main Authors: Mazhab-Jafari, Mohammad T., Rohou, Alexis, Schmidt, Carla, Bueler, Stephanie A., Benlekbir, Samir, Robinson, Carol V., Rubinstein, John L.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332345/
https://ncbi.nlm.nih.gov/pubmed/27776355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19828
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