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Automated task training and longitudinal monitoring of mouse mesoscale cortical circuits using home cages

We report improved automated open-source methodology for head-fixed mesoscale cortical imaging and/or behavioral training of home cage mice using Raspberry Pi-based hardware. Staged partial and probabilistic restraint allows mice to adjust to self-initiated headfixation over 3 weeks’ time with ~50%...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Murphy, Timothy H, Michelson, Nicholas J, Boyd, Jamie D, Fong, Tony, Bolanos, Luis A, Bierbrauer, David, Siu, Teri, Balbi, Matilde, Bolanos, Federico, Vanni, Matthieu, LeDue, Jeff M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332290/
https://ncbi.nlm.nih.gov/pubmed/32412409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55964
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