Omega-3 fatty acids activate ciliary FFAR4 to control adipogenesis

Adult mesenchymal stem cells, including preadipocytes, possess a cellular sensory organelle called the primary cilium. Ciliated preadipocytes abundantly populate perivascular compartments in fat and are activated by high fat diet. Here, we sought to understand if preadipocytes use their cilia to sen...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Hilgendorf, Keren I., Johnson, Carl T., Mezger, Anja, Rice, Selena L., Norris, Alessandra M., Demeter, Janos, Greenleaf, William J., Reiter, Jeremy F., Kopinke, Daniel, Jackson, Peter K.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332222/
https://ncbi.nlm.nih.gov/pubmed/31761534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.11.005
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