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Induction of fatigue-like behavior by pelvic irradiation of male mice alters cognitive behaviors and BDNF expression

Fatigue and cognitive deficits are often co-occurring symptoms reported by patients after radiation therapy for prostate cancer. In this study, we induced fatigue-like behavior in mice using targeted pelvic irradiation to mimic the clinical treatment regimen and assess cognitive behavioral changes....

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Pubblicato in:PLoS One
Autori principali: Wolff, Brian S., Raheem, Sumiyya A., Alshawi, Sarah A., Regan, Jeniece M., Feng, Li Rebekah, Saligan, Leorey N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332074/
https://ncbi.nlm.nih.gov/pubmed/32614931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235566
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