Effects of Acute versus Recurrent Insulin-Induced Hypoglycemia on Ventromedial Hypothalamic Nucleus Metabolic-Sensory Neuron AMPK Activity: Impact of Alpha(1)-Adrenergic Receptor Signaling

Mechanisms that underlie metabolic sensor acclimation to recurring insulin-induced hypoglycemia (RIIH) are unclear. Norepinephrine (NE) regulates ventromedial hypothalamic nucleus (VMN) gluco-stimulatory nitric oxide (NO) and gluco-inhibitory γ-aminobutryic acid (GABA) neuron signaling. Current rese...

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Bibliographic Details
Published in:Brain Res Bull
Main Authors: Briski, Karen P., Mandal, Santosh K., Bheemanapally, Khaggeswar, Ibrahim, Mostafa M.H.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332013/
https://ncbi.nlm.nih.gov/pubmed/31981674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2020.01.013
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