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Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44

Many targeting strategies can be employed to direct nanoparticles to tumors for imaging and therapy. However, tumors display a dynamic, heterogeneous microenvironment that undergoes spatiotemporal changes, including the expression of targetable cell-surface biomarkers. Here, we develop a nanoparticl...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Bhattacharya, Deep S., Svechkarev, Denis, Bapat, Aishwarya, Patil, Prathamesh, Hollingsworth, Michael A., Mohs, Aaron M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331950/
https://ncbi.nlm.nih.gov/pubmed/32617404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.0c00115
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