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Anti-apoptotic Actions of Allopregnanolone and Ganaxolone Mediated Through Membrane Progesterone Receptors (PAQRs) in Neuronal Cells

The neurosteroids progesterone and allopregnanolone regulate numerous neuroprotective functions in neural tissues including inhibition of epileptic seizures and cell death. Many of progesterone's actions are mediated through the nuclear progesterone receptor (PR), while allopregnanolone is wide...

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Publicat a:Front Endocrinol (Lausanne)
Autors principals: Thomas, Peter, Pang, Yefei
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331777/
https://ncbi.nlm.nih.gov/pubmed/32670200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00417
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