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Disease-related cellular protein networks differentially affected under different EGFR mutations in lung adenocarcinoma

It is unclear how epidermal growth factor receptor EGFR major driver mutations (L858R or Ex19del) affect downstream molecular networks and pathways. This study aimed to provide information on the influences of these mutations. The study assessed 36 protein expression profiles of lung adenocarcinoma...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Nishimura, Toshihide, Nakamura, Haruhiko, Yachie, Ayako, Hase, Takeshi, Fujii, Kiyonaga, Koizumi, Hirotaka, Naruki, Saeko, Takagi, Masayuki, Matsuoka, Yukiko, Furuya, Naoki, Kato, Harubumi, Saji, Hisashi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331587/
https://ncbi.nlm.nih.gov/pubmed/32616892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67894-7
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