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Angiotensin II receptor 1 antibodies associate with post-transplant focal segmental glomerulosclerosis and proteinuria

BACKGROUND: Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, endothelial and other cells, and play an essential role in the maintenance of podocyte function and vascular homeostasis. The presence of AT1R antibodies (AT1R-Abs) leads to activation of these receptors resulting in pod...

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Détails bibliographiques
Publié dans:BMC Nephrol
Auteurs principaux: Abuzeineh, Mohammad, Aala, Amtul, Alasfar, Sami, Alachkar, Nada
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331243/
https://ncbi.nlm.nih.gov/pubmed/32615995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-01910-w
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