Synthesis of Heteroannulated Indolopyrazines through Domino N–H Palladium-Catalyzed/Metal-Free Oxidative C–H Bond Activation

[Image: see text] A convenient approach to [1,2,5]oxadiazolo[3′,4′:5,6]pyrazino[2,3-b]indoles and their heteroannulated analogues bearing various aryl substituents in the backbone has been developed. This synthetic protocol is based on Pd-catalyzed Buchwald–Hartwig and subsequent annulation by intra...

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Vydáno v:ACS Omega
Hlavní autoři: Kvashnin, Yuriy A., Verbitskiy, Egor V., Zhilina, Ekaterina F., Rusinov, Gennady L., Chupakhin, Oleg N., Charushin, Valery N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331205/
https://ncbi.nlm.nih.gov/pubmed/32637843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01945
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