Bolus injections of novel thrombogenic site-targeted fusion proteins comprising annexin-V and Kunitz protease inhibitors attenuate intimal hyperplasia after balloon angioplasty

BACKGROUND: Systemic administrations of conventional antithrombotics reduce neointima formation after angioplasty in experimental animals. However, clinical translation of these results has not been successful due to high risk for bleeding. OBJECTIVES: We sought to determine whether novel annexin-V...

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Vydáno v:Int J Cardiol
Hlavní autoři: Yeh, Yung-Hsin, Chang, Shang-Hung, Chen, Shin-Yu, Wen, Chih-Jen, Wei, Fu-Chan, Tang, Rui, Achilefu, Sam, Wun, Tze-Chein, Chen, Wei-Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331180/
https://ncbi.nlm.nih.gov/pubmed/28433556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2017.03.150
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