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Development of a Pemetrexed/Folic Acid Nanoformulation: Synthesis, Characterization, and Efficacy in a Murine Colorectal Cancer Model

[Image: see text] The folate analogue pemetrexed (PEM) is an approved therapeutic for non-small cell lung cancer and malignant pleural mesothelioma with the potential for broader application in combination therapies. Here, we report the development of a nanoformulation of PEM and its efficacy agains...

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Publié dans:ACS Omega
Auteurs principaux: Rosch, Justin G., DuRoss, Allison N., Landry, Madeleine R., Sun, Conroy
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331029/
https://ncbi.nlm.nih.gov/pubmed/32637817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01550
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