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An adiponectin-S1P autocrine axis protects skeletal muscle cells from palmitate-induced cell death

BACKGROUND: The prevalence of type 2 diabetes, obesity and their various comorbidities have continued to rise. In skeletal muscle lipotoxicity is well known to be a contributor to the development of insulin resistance. Here it was examined if the small molecule adiponectin receptor agonist AdipoRon...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Lipids Health Dis
Prif Awduron: Botta, Amy, Elizbaryan, Kazaros, Tashakorinia, Parastoo, Lam, Nhat Hung, Sweeney, Gary
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330982/
https://ncbi.nlm.nih.gov/pubmed/32611437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-020-01332-5
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