Transcription factor EGR-1 transactivates the MMP1 gene promoter in response to TNFα in HaCaT keratinocytes

Matrix metalloproteinase 1 (MMP-1), a calcium-dependent zinc- containing collagenase, is involved in the initial degradation of native fibrillar collagen. Tissue necrosis factor-alpha (TNFα) is a pro-inflammatory cytokine that is rapidly produced by dermal fibroblasts, monocytes/macrophages, and ker...

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Veröffentlicht in:BMB Rep
Hauptverfasser: Yeo, Hyunjin, Lee, Jeong Yeon, Kim, JuHwan, Ahn, Sung Shin, Jeong, Jeong You, Choi, Ji Hye, Lee, Young Han, Shin, Soon Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Biochemistry and Molecular Biology 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330807/
https://ncbi.nlm.nih.gov/pubmed/32317080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2020.53.6.290
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