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Inhibition of miR-25 attenuates doxorubicin-induced apoptosis, reactive oxygen species production and DNA damage by targeting PTEN

Background: Doxorubicin (DOX) is one of the widely used anti-cancer drugs, whereas it can induce irreversible cardiac injury in a dose-dependent manner which limits its utility in clinic. Our study aimed to investigate the relationship between miR-25 and DOX-induced cardiac injury and its underlying...

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Détails bibliographiques
Publié dans:Int J Med Sci
Auteurs principaux: Li, Zhiqiang, Li, Hongqiang, Liu, Baoxin, Luo, Jiachen, Qin, Xiaoming, Gong, Mengmeng, Shi, Beibei, Wei, Yidong
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330660/
https://ncbi.nlm.nih.gov/pubmed/32624698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.41980
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