Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and β-catenin induction in mesothelium

Asbestos is still a social burden worldwide as a carcinogen causing malignant mesothelioma. Whereas recent studies suggest that local iron reduction is a preventive strategy against carcinogenesis, little is known regarding the cellular and molecular mechanisms surrounding excess iron. Here by diffe...

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Vydáno v:Redox Biol
Hlavní autoři: Ito, Fumiya, Yanatori, Izumi, Maeda, Yuki, Nimura, Kenta, Ito, Satoki, Hirayama, Tasuku, Nagasawa, Hideko, Kohyama, Norihiko, Okazaki, Yasumasa, Akatsuka, Shinya, Toyokuni, Shinya
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330611/
https://ncbi.nlm.nih.gov/pubmed/32863225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101616
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