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Klotho: An Elephant in Aging Research

The year 2017 marked the 20th anniversary of the first publication describing Klotho. This single protein was and is remarkable in that its absence in mice conferred an accelerated aging, or progeroid, phenotype with a dramatically shortened life span. On the other hand, genetic overexpression exten...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Cheikhi, Amin, Barchowsky, Aaron, Sahu, Amrita, Shinde, Sunita N, Pius, Abish, Clemens, Zachary J, Li, Hua, Kennedy, Charles A, Hoeck, Joerg D, Franti, Michael, Ambrosio, Fabrisia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330474/
https://ncbi.nlm.nih.gov/pubmed/30843026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz061
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