Mechanisms of resistance to osimertinib

The introduction of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) has significantly improved the prognosis of advanced non-small cell lung cancer (NSCLC) patients with EGFR mutations. The most common mechanism of acquired resistance to first- and second-generation EGFR TKIs...

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Vydáno v:J Thorac Dis
Hlavní autoři: Lazzari, Chiara, Gregorc, Vanesa, Karachaliou, Niki, Rosell, Rafael, Santarpia, Mariacarmela
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2020
Témata:
Review Article on Mechanisms of Resistance to EGFR-targeted Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330330/
https://ncbi.nlm.nih.gov/pubmed/32642198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2019.08.30
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