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Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency

Germ cell depletion in recipient testes is indispensable for successful transplantation of spermatogonial stem cells. However, we found that such treatment had an adverse effect on spermatogenesis of orthotopically transplanted donor testis tissues. In the donor tissue, the frequency of stimulated b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tsuchimoto, Akihiro, Tone, Masaaki, Ogonuki, Narumi, Hada, Masashi, Ogura, Atsuo, Takashima, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330030/
https://ncbi.nlm.nih.gov/pubmed/32612133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67595-1
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