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In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug–drug interactions

BACKGROUND: Inhibition of cytochrome P450 (CYP) enzymes is the most common cause of harmful drug–drug interactions. The present study aimed at examining the inhibitory effect of the novel antipsychotic drug asenapine on the main CYP enzymes in human liver. METHODS: The experiments were performed in...

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Gorde:
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Argitaratua izan da:Pharmacol Rep
Egile Nagusiak: Wójcikowski, Jacek, Danek, Przemysław J., Basińska-Ziobroń, Agnieszka, Pukło, Renata, Daniel, Władysława A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329795/
https://ncbi.nlm.nih.gov/pubmed/32219694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-020-00089-z
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