Chromatin 3D structure reconstruction with consideration of adjacency relationship among genomic loci

BACKGROUND: Chromatin 3D conformation plays important roles in regulating gene or protein functions. High-throughout chromosome conformation capture (3C)-based technologies, such as Hi-C, have been exploited to acquire the contact frequencies among genomic loci at genome-scale. Various computational...

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Udgivet i:BMC Bioinformatics
Main Authors: Li, Fang-Zhen, Liu, Zhi-E, Li, Xiu-Yuan, Bu, Li-Mei, Bu, Hong-Xia, Liu, Hui, Zhang, Cai-Ming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329537/
https://ncbi.nlm.nih.gov/pubmed/32611376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03612-4
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