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Knockdown of LAP2α inhibits osteogenic differentiation of human adipose-derived stem cells by activating NF-κB

BACKGROUND: Lamina-associated polypeptide 2α (LAP2α) is a nucleoplasmic protein that has been involved in the regulation of the cell cycle, gene transcription, and adult stem cell function. LAP2α down-regulation is linked to age-related osteoporosis and bone deformities; however, the underlying mech...

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Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Tang, Yiman, Zhang, Xiao, Ge, Wenshu, Zhou, Yongsheng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329510/
https://ncbi.nlm.nih.gov/pubmed/32611381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01774-9
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