Comparative RNA-Seq transcriptome analyses reveal dynamic time-dependent effects of (56)Fe, (16)O, and (28)Si irradiation on the induction of murine hepatocellular carcinoma

BACKGROUND: One of the health risks posed to astronauts during deep space flights is exposure to high charge, high-energy (HZE) ions (Z > 13), which can lead to the induction of hepatocellular carcinoma (HCC). However, little is known on the molecular mechanisms of HZE irradiation-induced HCC. RE...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Nia, Anna M., Khanipov, Kamil, Barnette, Brooke L., Ullrich, Robert L., Golovko, George, Emmett, Mark R.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329445/
https://ncbi.nlm.nih.gov/pubmed/32611366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-06869-4
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