Fragile X Mental Retardation Protein Bidirectionally Controls Dendritic I(h) in a Cell Type-Specific Manner between Mouse Hippocampus and Prefrontal Cortex

Channelopathies are implicated in Fragile X syndrome (FXS), yet the dysfunction of a particular ion channel varies with cell type. We previously showed that HCN channel function is elevated in CA1 dendrites of the fmr1(–/y) mouse model of FXS, but reduced in L5 PFC dendrites. Using male mice, we tes...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Brandalise, Federico, Kalmbach, Brian E., Mehta, Preeti, Thornton, Olivia, Johnston, Daniel, Zemelman, Boris V., Brager, Darrin H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329306/
https://ncbi.nlm.nih.gov/pubmed/32467357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1670-19.2020
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