Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster

Physical resiliency declines with age and comorbid conditions. In humans, angiotensin-converting enzyme (ACE) has been associated with attenuation of the decline in physical performance with age. ACE-inhibitor compounds, commonly prescribed for hypertension, often have beneficial effects on physical...

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Pubblicato in:J Gerontol A Biol Sci Med Sci
Autori principali: Gabrawy, Mariann M, Campbell, Sarah, Carbone, Mary Anna, Morozova, Tatiana V, Arya, Gunjan H, Turlapati, Lavanya B, Walston, Jeremy D, Starz-Gaiano, Michelle, Everett, Logan, Mackay, Trudy F C, Leips, Jeff, Abadir, Peter M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
The Journal of Gerontology: Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329186/
https://ncbi.nlm.nih.gov/pubmed/31197356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz152
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